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T Tomita Selected Research

Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

8/2011Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis.
7/2010TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derived from a fraction of patients with rheumatoid arthritis.
9/2001Induction of fibroblast-like cells from CD34(+) progenitor cells of the bone marrow in rheumatoid arthritis.
3/2001Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis.
7/2000Transcription factor decoy for NFkappaB inhibits cytokine and adhesion molecule expressions in synovial cells derived from rheumatoid arthritis.
5/2000Expression of eotaxin by normal airway epithelial cells after influenza virus A infection.
2/2000IL-6 inhibits the proliferation of fibroblastic synovial cells from rheumatoid arthritis patients in the presence of soluble IL-6 receptor.

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T Tomita Research Topics

Disease

12Neoplasms (Cancer)
03/2016 - 04/2000
9Rheumatoid Arthritis
01/2013 - 02/2000
6Alzheimer Disease (Alzheimer's Disease)
08/2001 - 03/2000
5Inflammation (Inflammations)
08/2014 - 04/2001
5Necrosis
01/2013 - 07/2000
5Osteoarthritis
07/2010 - 01/2000
4Neoplasm Metastasis (Metastasis)
04/2014 - 08/2000
4Infections
04/2002 - 01/2000
4Squamous Cell Carcinoma of Head and Neck
10/2000 - 04/2000
3Insulin Resistance
12/2011 - 05/2006
3Insulinoma
05/2006 - 04/2000
3Glucagonoma
05/2006 - 04/2000
3Gastrinoma
05/2006 - 04/2000
3Head and Neck Neoplasms (Head and Neck Cancer)
07/2001 - 08/2000
2Pain (Aches)
11/2016 - 04/2000
2Glioblastoma (Glioblastoma Multiforme)
10/2016 - 01/2016
2Stomach Neoplasms (Stomach Cancer)
08/2014 - 02/2013
2Dyspepsia (Indigestion)
01/2012 - 11/2009
2Body Weight (Weight, Body)
08/2010 - 12/2001
2Hyperplasia
07/2010 - 07/2000
2Wounds and Injuries (Trauma)
01/2010 - 08/2006
2Hypoxia (Hypoxemia)
01/2010 - 04/2001
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
12/2005 - 08/2003
2Crohn Disease (Crohn's Disease)
12/2005 - 06/2001
2Hyperventilation
04/2003 - 03/2000
2Tendinopathy (Tendonitis)
06/2001 - 10/2000
2Atherosclerosis
01/2001 - 04/2000
1Lewis Lung Carcinoma
03/2016
1Cysts
01/2016
1Carcinogenesis
08/2014
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
07/2014
1Peptic Esophagitis (Reflux Esophagitis)
07/2014
1Periodontitis
06/2014
1Hemorrhage
06/2014
1Rheumatic Diseases (Rheumatism)
01/2013
1Hypersensitivity (Allergy)
01/2012
1Metabolic Syndrome (Dysmetabolic Syndrome X)
12/2011

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
01/2016 - 05/2000
9Messenger RNA (mRNA)IBA
06/2014 - 08/2000
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2011 - 02/2000
5Amyloid beta-PeptidesIBA
06/2014 - 11/2000
4Biological ProductsIBA
01/2016 - 01/2013
4Insulin (Novolin)FDA Link
12/2011 - 08/2001
4CytokinesIBA
07/2010 - 07/2000
4AutoantibodiesIBA
08/2003 - 08/2000
4Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
09/2001 - 01/2000
4PresenilinsIBA
08/2001 - 03/2000
3Biomarkers (Surrogate Marker)IBA
02/2013 - 04/2000
3AcidsIBA
01/2012 - 06/2001
3Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2001 - 04/2001
3Peptides (Polypeptides)IBA
01/2001 - 04/2000
3Matrix Metalloproteinases (MMPs)IBA
08/2000 - 04/2000
2DNA (Deoxyribonucleic Acid)IBA
10/2016 - 01/2016
2Interleukin-1beta (Interleukin 1 beta)IBA
06/2014 - 03/2001
2Glucose (Dextrose)FDA LinkGeneric
12/2011 - 05/2006
2LigandsIBA
08/2011 - 01/2008
2Amyloid (Amyloid Fibrils)IBA
08/2011 - 11/2000
2Interleukin-18 (Interleukin 18)IBA
12/2005 - 02/2001
2Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
04/2003 - 01/2001
2Proprotein Convertase 1IBA
08/2001 - 01/2001
2Pancreatic Polypeptide (Pancreatic Polypeptide (PP))IBA
08/2001 - 04/2000
2Fluorouracil (Carac)FDA LinkGeneric
07/2001 - 10/2000
2beta-DefensinsIBA
07/2001 - 01/2000
2DefensinsIBA
07/2001 - 01/2000
2Nitric Oxide Synthase (NO Synthase)IBA
04/2001 - 04/2001
2Protein Isoforms (Isoforms)IBA
04/2001 - 04/2000
2Peptide Hydrolases (Proteases)FDA Link
03/2001 - 08/2000
2TeaIBA
01/2001 - 04/2000
2LipidsIBA
01/2001 - 11/2000
2Flavin-Adenine Dinucleotide (FAD)IBA
11/2000 - 06/2000
2Carboplatin (JM8)FDA LinkGeneric
10/2000 - 09/2000
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
08/2000 - 08/2000
2Matrix Metalloproteinase 14 (MT1-MMP)IBA
08/2000 - 08/2000
1Local AnestheticsIBA
11/2016
1eritoranIBA
03/2016
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2016
1interleukin-22 receptor (IL-22R)IBA
08/2014
1Small Interfering RNA (siRNA)IBA
08/2014
1Interleukin-22 (IL-22)IBA
08/2014
1Substance PIBA
07/2014
1liu-jun-zi-tangIBA
07/2014
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
06/2014
1Complement C1 (Complement 1)IBA
06/2014
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
06/2014
1RNA (Ribonucleic Acid)IBA
06/2014
1DisintegrinsIBA
04/2014
1Ephrin-A1 (Ephrin A1)IBA
04/2014
1Metalloproteases (Metalloproteinases)IBA
04/2014
1Neutralizing AntibodiesIBA
04/2014
1S-1 plus cisplatinIBA
02/2013
1tocilizumab (atlizumab)FDA Link
01/2013
1Antirheumatic Agents (DMARD)IBA
01/2013
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
02/2012
1azilsartanIBA
12/2011
1Toll-Like Receptor 4IBA
08/2011
1naphthaleneIBA
08/2011
1Fatty Acids (Saturated Fatty Acids)IBA
08/2010

Therapy/Procedure

4Drug Therapy (Chemotherapy)
01/2016 - 09/2000
4Therapeutics
06/2006 - 02/2001
2Radiotherapy
11/2000 - 05/2000